Erwin W Gelfand Selected Research

Metaplasia

6/2016	Immunomodulatory Effects of Ambroxol on Airway Hyperresponsiveness and Inflammation.
10/2015	Contrasting roles for the receptor for advanced glycation end-products on structural cells in allergic airway inflammation vs. airway hyperresponsiveness.
1/2013	Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses.
10/2012	Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing T(H)2 and T(H)17 T-cell differentiation.
4/2012	Inhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammation.
8/2010	Montelukast during primary infection prevents airway hyperresponsiveness and inflammation after reinfection with respiratory syncytial virus.
8/2010	Peanut-induced intestinal allergy is mediated through a mast cell-IgE-FcepsilonRI-IL-13 pathway.
9/2009	Differential effects of dendritic cell transfer on airway hyperresponsiveness and inflammation.
7/2009	Vaccine-induced CD8+ T cell-dependent suppression of airway hyperresponsiveness and inflammation.
1/2009	Mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2-dependent pathways are essential for CD8+ T cell-mediated airway hyperresponsiveness and inflammation.

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Erwin W Gelfand Research Topics

Disease

87	Inflammation (Inflammations) 07/2021 - 04/2002
76	Respiratory Hypersensitivity 01/2019 - 03/2002
58	Asthma (Bronchial Asthma) 01/2021 - 07/2002
24	Eosinophilia 06/2016 - 04/2002
16	Infections 01/2022 - 09/2003
16	Metaplasia 06/2016 - 01/2006
13	Pneumonia (Pneumonitis) 11/2016 - 07/2002
9	Hypersensitivity (Allergy) 01/2018 - 11/2004
9	Hyperplasia 09/2006 - 11/2002
6	Respiratory Syncytial Virus Infections 07/2014 - 03/2002
6	Allergic Rhinitis 01/2013 - 03/2005
5	Emphysema 07/2021 - 01/2013
5	Reinfection 07/2014 - 08/2005
4	Peanut Hypersensitivity (Peanut Allergy) 01/2018 - 10/2012
4	Virus Diseases (Viral Diseases) 11/2015 - 11/2003
4	Neoplasms (Cancer) 01/2014 - 09/2003
3	Anaphylaxis (Anaphylactic Shock) 01/2020 - 11/2013
3	Lymphopenia (Lymphocytopenia) 12/2018 - 08/2014
3	Lung Diseases (Lung Disease) 11/2018 - 01/2011
3	Ectodermal Dysplasia (Aplasia Cutis Congenita) 01/2018 - 06/2008
3	Atopic Dermatitis (Atopic Eczema) 08/2017 - 12/2008
3	Airway Remodeling 06/2017 - 09/2006
3	Primary Immunodeficiency Diseases 11/2015 - 03/2005
2	Interstitial Lung Diseases (Interstitial Lung Disease) 07/2022 - 09/2003
2	Cytopenia 07/2019 - 01/2019
2	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 07/2019 - 11/2015
2	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2019 - 01/2019
2	Granuloma 01/2019 - 01/2019
2	Diarrhea 01/2018 - 11/2013
2	Chronic Obstructive Pulmonary Disease (COPD) 06/2017 - 06/2016
2	Disease Progression 11/2016 - 01/2013
2	Pulmonary Emphysema 11/2016 - 01/2013
2	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 08/2014 - 06/2007
2	Breast Neoplasms (Breast Cancer) 01/2014 - 02/2004

Drug/Important Bio-Agent (IBA)

59	AllergensIBA 01/2020 - 03/2002
46	CytokinesIBA 01/2020 - 03/2002
32	Interleukin-13IBA 01/2020 - 12/2002
24	Methacholine Chloride (Methacholine)FDA Link 01/2019 - 03/2002
16	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2019 - 07/2004
14	Proteins (Proteins, Gene)FDA Link 07/2021 - 09/2003
14	OvalbuminIBA 06/2016 - 07/2002
12	Immunoglobulin E (IgE)IBA 01/2019 - 07/2002
9	InterleukinsIBA 12/2019 - 10/2003
9	SteroidsIBA 07/2019 - 07/2003
9	Leukotriene B4IBA 03/2014 - 04/2005
8	Interleukin-4 (Interleukin 4)IBA 01/2019 - 02/2004
8	Interleukin-5 (Interleukin 5)IBA 02/2015 - 03/2002
7	LeukotrienesIBA 01/2021 - 06/2006
7	Messenger RNA (mRNA)IBA 01/2018 - 11/2004
6	ChemokinesIBA 04/2015 - 09/2003
5	Phosphotransferases (Kinase)IBA 07/2022 - 04/2012
5	Pancreatic Elastase (Elastase)IBA 07/2021 - 01/2013
5	Immunoglobulin G (IgG)IBA 07/2021 - 12/2003
5	EnzymesIBA 01/2020 - 05/2013
5	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 03/2014 - 07/2005
5	AntigensIBA 01/2012 - 02/2004
4	NF-kappa B (NF-kB)IBA 07/2022 - 04/2008
4	Intravenous Immunoglobulins (IVIG)FDA Link 01/2022 - 11/2005
4	Cholesterol Side-Chain Cleavage Enzyme (CYP11A1)IBA 01/2020 - 05/2013
4	VaccinesIBA 11/2015 - 07/2009
4	Interleukin-10 (Interleukin 10)IBA 02/2015 - 02/2007
4	AntibodiesIBA 07/2014 - 05/2004
4	Leukotriene E4IBA 12/2011 - 05/2006
4	OzoneIBA 01/2010 - 03/2004
4	Histamine Antagonists (Antihistamines)IBA 01/2008 - 07/2002
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 07/2022 - 05/2004
3	SmokeIBA 07/2021 - 08/2011
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 10/2002
3	Immunoglobulins (Immunoglobulin)IBA 01/2019 - 03/2005
3	p38 Mitogen-Activated Protein KinasesIBA 11/2013 - 06/2004
3	Histamine (Histamine Dihydrochloride)FDA Link 01/2013 - 12/2002
3	montelukast (Singulair)FDA Link 08/2012 - 04/2006
3	Complement System Proteins (Complement)IBA 01/2012 - 12/2003
3	Albuterol (Salbutamol)FDA LinkGeneric 12/2011 - 03/2006
3	IgE Receptors (Fc epsilon RI)IBA 01/2009 - 05/2004
3	Chemokine CCL5IBA 08/2006 - 09/2003
3	fexofenadine (Allegra)FDA LinkGeneric 10/2003 - 07/2002
2	IgG Receptors (Fc gamma RI)IBA 07/2022 - 01/2007
2	Rituximab (Mabthera)FDA Link 07/2019 - 01/2019
2	Interleukin-2 (IL2)IBA 01/2019 - 03/2007
2	Immunoglobulin M (IgM)IBA 01/2019 - 01/2019
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2019 - 03/2004
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018 - 04/2008
2	Mitogen-Activated Protein KinasesIBA 06/2017 - 01/2009
2	Interleukin-17 (Interleukin 17)IBA 11/2016 - 01/2013
2	Surface-Active Agents (Surfactants)IBA 06/2016 - 09/2003
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2015 - 05/2009
2	Receptor for Advanced Glycation End ProductsIBA 10/2015 - 04/2015
2	Monoclonal AntibodiesIBA 07/2014 - 05/2004
2	Estrogens (Estrogen)FDA Link 01/2014 - 05/2008
2	Hormones (Hormone)IBA 01/2014 - 05/2008
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2014 - 02/2004
2	AerosolsIBA 01/2013 - 10/2011
2	Interleukin-12 (IL 12)IBA 11/2012 - 10/2003
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 10/2012 - 11/2002
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 08/2012 - 04/2005
2	Dexamethasone (Maxidex)FDA LinkGeneric 08/2012 - 04/2008

Therapy/Procedure

19	Therapeutics 07/2019 - 07/2003
2	Transplantation 01/2017 - 04/2014
2	Ligation 05/2012 - 01/2009